--- title: Research Scientist I / II High Throughput Chemistry description: Iambic is hiring for the Research Scientist I / II High Throughput Chemistry role in San Diego, CA. See the full description and apply. type: job url: https://www.foundrole.com/jobs/research-scientist-i-ii-high-throughput-chemistry-at-iambic-01a0d59c-eea6-79c6-865e-730cd13a9ad4 date: 2026-11-13T11:20:05Z og_description: Join Iambic as Research Scientist I / II High Throughput Chemistry in San Diego, CA. Pays $113K–$156K per year. og_image: https://www.foundrole.com/og/vp78ga.png breadcrumbs: - label: Home url: https://www.foundrole.com/ - label: Search url: https://www.foundrole.com/jobs --- | | | |---|---| | **Company** | Iambic | | **Location** | San Diego, CA | | **Salary** | $113K/yr - $156K/yr | | **Type** | Full Time | | **Posted** | Sep 25, 2026 | ## Is this job real? **Ghost job check:** A- · Low risk. Probably a real opening. ## Visa sponsorship - **H-1B:** Iambic sponsors H-1B visas. It filed 1 H-1B petition (FY2026 Q1 – FY2026 Q4). - **E-Verify:** No E-Verify enrollment on record for Iambic. ## Pay for similar jobs Most similar jobs pay $83,000 – $147,000 a year (median $106,000). ## Description JOB SUMMARY We are seeking a highly skilled and motivated Research Scientist to join our Discovery Chemistry team at Iambic Therapeutics in San Diego, CA. In this role, the ideal candidate will exploit their strong background in organic synthesis, catalysis, and reaction development to design, optimize, and execute high-throughput experiments to drive compound library campaigns. The successful candidate will deliver impact cross-functionally with chemistry, biology, compound management, AI/ML, and software teams across the discovery pipeline, leveraging Iambic's HTE platform to accelerate and strengthen our programs. This position will be based in our San Diego Headquarters. KEY RESPONSIBILITIES - Design and execute parallel synthetic methods to generate large, high-quality compound libraries. - Identify, develop, and optimize novel synthetic methodologies with a focus on automation compatibility and HTE scalability. - Apply newly developed synthetic routes from traditional bench-scale chemistry to robust, high-throughput, and automated processes. - Oversee the operation, maintenance, and continuous advancement of our chemistry toolkit and automated synthesis equipment. - Analyze research outcomes and library compound data and clearly communicate results and findings to cross-functional project teams. - Ensure all laboratory work is conducted in accordance with established safety protocols and best laboratory and ELN data recording practices. - Function as a core member of an interdisciplinary scientific team (chemistry, biology, software, and automation). - Proactively identify bottlenecks, troubleshoot automated processes, and develop solutions to ensure business continuity. QUALIFICATIONS Required: - Ph.D. in Organic Chemistry with 0-5 years of industry experience or MS in Organic Chemistry with a minimum of 8 years of industry experience. - Strong command of modern organic synthetic methods. - Direct hands-on experience with High Throughput Chemistry and/or Parallel Synthesis. - Experience with laboratory automation, liquid handling robotics, and automated analytical and purification systems. - Ability to thrive in a fast-paced, highly collaborative, and dynamic research environment. - Excellent written and verbal communication skills; must be able to articulate complex scientific concepts, technical challenges, and results clearly and concisely to diverse audiences. - Proven ability to thrive in a fast-paced, high-volume environment where priorities and synthetic targets may shift rapidly based on biological data. Strongly Preferred: - Experience with Direct-to-Biology (D2B) strategies for drug discovery. - Familiarity with the principles of medicinal chemistry. - Prior experience mentoring interns or junior colleagues. ABOUT IAMBIC THERAPEUTICS Iambic Therapeutics (Nasdaq: IAM) is a technology and clinical-stage life sciences company headquartered in San Diego. By utilizing molecular superintelligence — integrating proprietary AI with automated, scalable chemistry and biology experimentation — our platform is designed to address the totality of drug discovery and development. At Iambic, we are building an engine that is designed to power the future of medicine. Learn more at [iambic.ai](http://iambic.ai). MISSION & VALUES Our mission is to make better technology for better medicines. Three values guide how we work: - Bold. We are courageous, take thoughtful risks, and approach challenges with tenacity. - Innovative. We are creative and find new solutions that deliver impact. - Collaborative. We respect one another and partner with integrity. We value the range of perspectives our people bring, and we work to build an environment where every team member can contribute and grow. PAY AND BENEFITS The pay range for this role is listed above. Actual pay depends on factors including experience, skills, and location. Eligible employees in the U.S. receive company-paid medical coverage, flexible spending accounts, voluntary life insurance, 401(k) matching and flexible time off. We are in a brand-new state-of-the art facility in beautiful San Diego with a community gym, dining, and easy access to great places to live and play. EQUAL OPPORTUNITY Iambic is an equal opportunity employer. We consider all qualified applicants without regard to race, color, religion, sex, sexual orientation, gender identity or expression, national origin, ancestry, age, disability, medical condition, genetic information, marital status, veteran or military status, or any other characteristic protected by law.   ## Skills - Robotics - Medicinal Chemistry - High-Throughput Screening - Automation - Scalability - Safety Procedures - Mentoring - Liquid Handling - Drug Discovery - Maintenance - Chemical Processes - Communication - Highways - Laboratory Skills - Business Continuity ## Benefits - Health Insurance - Life Insurance - Paid Time Off (Pto) - 401(k) Plans ## Related - [Science & Research jobs](https://www.foundrole.com/careers/science-and-research?utm_source=ai_markdown)- [Biomedical & Population Health Research jobs](https://www.foundrole.com/careers/science-and-research/biomedical-and-population-health-research?utm_source=ai_markdown)- [Research Scientist jobs](https://www.foundrole.com/careers/science-and-research/biomedical-and-population-health-research/research-scientist?utm_source=ai_markdown)- [Browse all companies](https://www.foundrole.com/companies?utm_source=ai_markdown) ## Explore this job market - [California](https://www.foundrole.com/locations/us/california?utm_source=ai_markdown) — 260844 jobs - [Pharmaceutical Manufacturing](https://www.foundrole.com/sectors/pharmaceuticals-and-biotechnology/pharmaceutical-manufacturing?utm_source=ai_markdown) — 42025 jobs - [San Diego, CA](https://www.foundrole.com/locations/us/california/san-diego?utm_source=ai_markdown) — 15138 jobs ## Related pages - [California](https://www.foundrole.com/locations/us/california?utm_source=ai_markdown) — 260844 jobs - [Pharmaceutical Manufacturing](https://www.foundrole.com/sectors/pharmaceuticals-and-biotechnology/pharmaceutical-manufacturing?utm_source=ai_markdown) — 42025 jobs - [San Diego, CA](https://www.foundrole.com/locations/us/california/san-diego?utm_source=ai_markdown) — 15138 jobs ## Browse - [Companies](https://www.foundrole.com/companies?utm_source=ai_markdown) - [Jobs by country](https://www.foundrole.com/locations?utm_source=ai_markdown) - [Jobs in the United States by state and city](https://www.foundrole.com/locations/us?utm_source=ai_markdown) - [H1B sponsors by location](https://www.foundrole.com/h1b-sponsors?utm_source=ai_markdown) - [H1B salaries](https://www.foundrole.com/h1b-salaries?utm_source=ai_markdown) - [Sectors and industries](https://www.foundrole.com/sectors?utm_source=ai_markdown) - [Jobs by career field](https://www.foundrole.com/careers?utm_source=ai_markdown) - [Latest jobs](https://www.foundrole.com/jobs/latest?utm_source=ai_markdown)