--- title: NGS Senior Scientist 1 at Tempus AI in Chicago, IL description: Tempus AI is hiring for the NGS Senior Scientist 1 role in Chicago, IL. Pays $95K–$120K per year. See the full description and apply. type: job url: https://www.foundrole.com/jobs/ngs-senior-scientist-1-at-tempus-ai-01a0b24b-6cb1-715e-b582-ec57739182e4 date: 2026-11-15T01:26:44Z og_description: Join Tempus AI as NGS Senior Scientist 1 in Chicago, IL. Pays $95K–$120K per year. Full-time, hybrid role. og_image: https://www.foundrole.com/og/qtccfl.png breadcrumbs: - label: Home url: https://www.foundrole.com/ - label: Search url: https://www.foundrole.com/jobs --- | | | |---|---| | **Company** | [Tempus AI](https://www.foundrole.com/companies/tempus-ai?utm_source=ai_markdown) | | **Location** | Chicago, IL (Hybrid) | | **Salary** | $95K/yr - $120K/yr | | **Type** | Full Time | | **Posted** | Oct 06, 2026 | ## Is this job real? **Ghost job check:** A · Low risk. Probably a real opening. ## Visa sponsorship - **H-1B:** Tempus AI sponsors H-1B visas. It filed 55 H-1B petitions (FY2026 Q1 – FY2026 Q4). - **E-Verify:** No E-Verify enrollment on record for Tempus AI. ## Pay for similar jobs Most similar jobs pay $89,000 – $164,000 a year (median $130,000). ## Description **Passionate about precision medicine and advancing the healthcare industry?** Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time. We are seeking a **Senior Scientist** to lead the development and validation of new molecular assays and laboratory processes for deployment in our clinical laboratory. **What You’ll Do** - Lead development of molecular assays and NGS workflows for high-throughput clinical laboratories. - Design, execute, and analyze R&D studies with scientific rigor and attention to detail. - Lead assay validation and clinical implementation from study design through launch, including workflow development, SOP creation, and documentation. - Design and execute qualification and validation studies for reagents, instruments, equipment, and methods to support clinical deployment. - Interpret data, troubleshoot issues, and drive process improvements. - Collaborate across cross-functional teams and provide scientific leadership in a matrixed environment. - Communicate clearly and effectively with technical and non-technical stakeholders. - Train and mentor junior scientific staff and support implementation of new laboratory workflows. - Support automation and technology initiatives to improve laboratory workflows. - Manage multiple priorities and adapt quickly in a fast-paced environment. - Travel up to 10% as needed. **Qualifications** - Ph.D. with 0 or more years of experience, or Master’s degree with 5+ years of relevant experience in molecular biology, assay development, or a related field. - Experience in assay development and/or validation required. - Experience in a clinical laboratory environment required; CAP/CLIA/NYSDOH experience preferred. - Strong analytical, troubleshooting, and experimental design skills. - Highly organized, detail-oriented, and committed to quality and accuracy. - Proven ability to learn quickly and adapt to new processes, technologies, and workflows. - Strong collaboration skills with the ability to lead across teams. - Excellent oral and written communication skills. - Ability to manage competing priorities and deadlines in a dynamic environment. **Preferred Technical Experience** - DNA/RNA extraction and purification methods. - NGS library preparation, hybrid capture, and sequencing workflows. - PCR-based techniques, including PCR, qPCR, RT-PCR, and ddPCR. - Nucleic acid manipulation, quantitation, and analysis. - Assay troubleshooting, root cause analysis, and workflow optimization. **Highly Desirable** - Experience with liquid biopsy workflows. - Experience with laboratory automation and liquid handling robotics. - Experience developing and implementing protocols for CLIA-regulated laboratories. - Familiarity with LIMS and laboratory data systems. Pay Range: $95,000 - $120,000 USD The expected salary range may vary for other locations. Actual salary may vary based on qualifications and experience. Tempus offers a full range of benefits, which may include incentive compensation, restricted stock units, medical and other benefits depending on the position. We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status. ## Skills - Liquid Biopsy - Digital Droplet PCR - Experimental Design - Illumina Laboratory Information Management System LIMS - Robotics - High-Throughput Screening - Software Deployment - Process Optimization - Quantitative PCR (qPCR) - RNA Extraction - Automation - Root Cause Analysis - Assay Development - Collaboration - Assay Validation - Research Design - Liquid Handling - Polymerase Chain Reaction - Attention to Detail - Leadership - Written Communication - Organizational Skills - Chemical Processes - Standard Operating Procedure (Sop) Development - Detail Oriented ## Benefits - Health Insurance - Employee Stock Options (ESOs) ## Related - [More jobs at Tempus AI](https://www.foundrole.com/companies/tempus-ai?utm_source=ai_markdown) - [Science & Research jobs](https://www.foundrole.com/careers/science-and-research?utm_source=ai_markdown)- [Biomedical & Population Health Research jobs](https://www.foundrole.com/careers/science-and-research/biomedical-and-population-health-research?utm_source=ai_markdown)- [Research Scientist jobs](https://www.foundrole.com/careers/science-and-research/biomedical-and-population-health-research/research-scientist?utm_source=ai_markdown)- [Browse all companies](https://www.foundrole.com/companies?utm_source=ai_markdown) ## Explore this job market - [Illinois](https://www.foundrole.com/locations/us/illinois?utm_source=ai_markdown) — 101547 jobs - [Chicago, IL](https://www.foundrole.com/locations/us/illinois/chicago?utm_source=ai_markdown) — 29555 jobs - [Medical and Diagnostic Laboratories](https://www.foundrole.com/sectors/healthcare/medical-and-diagnostic-laboratories?utm_source=ai_markdown) — 14727 jobs - [Tempus AI](https://www.foundrole.com/companies/tempus-ai?utm_source=ai_markdown) — 272 jobs ## Related pages - [Illinois](https://www.foundrole.com/locations/us/illinois?utm_source=ai_markdown) — 101547 jobs - [Chicago, IL](https://www.foundrole.com/locations/us/illinois/chicago?utm_source=ai_markdown) — 29555 jobs - [Medical and Diagnostic Laboratories](https://www.foundrole.com/sectors/healthcare/medical-and-diagnostic-laboratories?utm_source=ai_markdown) — 14727 jobs - [Tempus AI](https://www.foundrole.com/companies/tempus-ai?utm_source=ai_markdown) — 272 jobs ## Browse - [Companies](https://www.foundrole.com/companies?utm_source=ai_markdown) - [Jobs by country](https://www.foundrole.com/locations?utm_source=ai_markdown) - [Jobs in the United States by state and city](https://www.foundrole.com/locations/us?utm_source=ai_markdown) - [H1B sponsors by location](https://www.foundrole.com/h1b-sponsors?utm_source=ai_markdown) - [H1B salaries](https://www.foundrole.com/h1b-salaries?utm_source=ai_markdown) - [Sectors and industries](https://www.foundrole.com/sectors?utm_source=ai_markdown) - [Jobs by career field](https://www.foundrole.com/careers?utm_source=ai_markdown) - [Latest jobs](https://www.foundrole.com/jobs/latest?utm_source=ai_markdown)